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Question 1
Correct
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A 32-year-old man from West Africa presents to his GP in January with symptoms of depression. He has no significant medical history but is a regular cannabis smoker. He has experienced similar episodes during the past two winters. What is the probable diagnosis?
Your Answer: Seasonal affective disorder
Explanation:Understanding Seasonal Affective Disorder
Seasonal affective disorder (SAD) is a type of depression that typically occurs during the winter months. It is important to treat SAD in the same way as depression, following the guidelines set out by the National Institute for Health and Care Excellence (NICE). This involves starting with psychological therapies and monitoring the patient’s progress after two weeks to ensure that their symptoms have not worsened. If necessary, an SSRI can be prescribed.
It is important to note that sleeping tablets should not be given to patients with SAD, as this can exacerbate their symptoms. While light therapy is often suggested as a treatment option, the evidence supporting its effectiveness is limited. As a result, it is not routinely recommended.
In summary, SAD is a form of depression that requires careful management and treatment. By following the appropriate guidelines and avoiding certain medications, patients can receive the support they need to manage their symptoms and improve their quality of life.
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This question is part of the following fields:
- Psychiatry
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Question 2
Incorrect
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Which one of the following is not a recognized feature of anorexia nervosa in adolescents?
Your Answer: Impaired glucose tolerance
Correct Answer: Reduced growth hormone levels
Explanation:Anorexia is characterized by low levels of various substances, including growth hormone, glucose, salivary glands, cortisol, cholesterol, and carotene.
Characteristics of Anorexia Nervosa
Anorexia nervosa is a disorder that is characterized by a number of clinical signs and physiological abnormalities. The most notable feature of this disorder is a reduced body mass index, which is often accompanied by bradycardia and hypotension. In addition, individuals with anorexia nervosa may experience enlarged salivary glands, which can cause discomfort and difficulty swallowing.
Physiological abnormalities associated with anorexia nervosa include hypokalaemia, which is a deficiency of potassium in the blood, as well as low levels of FSH, LH, oestrogens, and testosterone. Individuals with anorexia nervosa may also have raised levels of cortisol and growth hormone, impaired glucose tolerance, hypercholesterolaemia, hypercarotinaemia, and low T3.
Overall, anorexia nervosa is a complex disorder that can have a significant impact on an individual’s physical and emotional well-being. It is important for individuals who are struggling with this disorder to seek professional help in order to receive the support and treatment they need to recover.
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This question is part of the following fields:
- Psychiatry
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Question 3
Incorrect
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As a junior doctor in the Emergency Department, you encounter a 40-year-old woman who has been brought in by the police under a section 135. The police had to obtain a warrant as part of the process. The patient is currently agitated and speaking incoherently about religious phrases. She has a documented history of severe depression.
What powers does section 135 grant to the police in this situation?Your Answer: To bring a person with suspected mental health issues in from the community
Correct Answer: To bring a person with suspected mental health issues in from their property
Explanation:If the police believe that someone requires a mental health assessment or treatment, they can request a section 135 to remove the individual from their property. The procedure involves an Approved Mental Health Practitioner (AMHP) presenting evidence at a Magistrate’s Court to obtain a warrant. This warrant permits the Police, an AMHP, and a registered medical practitioner to enter the premises and conduct an assessment or take the person to a safe location for evaluation.
Sectioning under the Mental Health Act is a legal process used for individuals who refuse voluntary admission. This process excludes patients who are under the influence of drugs or alcohol. There are several sections under the Mental Health Act that allow for different types of admission and treatment.
Section 2 allows for admission for assessment for up to 28 days, which is not renewable. An Approved Mental Health Professional (AMHP) or the nearest relative (NR) can make the application on the recommendation of two doctors, one of whom should be an approved consultant psychiatrist. Treatment can be given against the patient’s wishes.
Section 3 allows for admission for treatment for up to 6 months, which can be renewed. An AMHP and two doctors, both of whom must have seen the patient within the past 24 hours, can make the application. Treatment can also be given against the patient’s wishes.
Section 4 is used as an emergency 72-hour assessment order when a section 2 would involve an unacceptable delay. A GP and an AMHP or NR can make the application, which is often changed to a section 2 upon arrival at the hospital.
Section 5(2) allows a doctor to legally detain a voluntary patient in hospital for 72 hours, while section 5(4) allows a nurse to detain a voluntary patient for 6 hours.
Section 17a allows for Supervised Community Treatment (Community Treatment Order) and can be used to recall a patient to the hospital for treatment if they do not comply with the conditions of the order in the community, such as taking medication.
Section 135 allows for a court order to be obtained to allow the police to break into a property to remove a person to a Place of Safety. Section 136 allows for someone found in a public place who appears to have a mental disorder to be taken by the police to a Place of Safety. This section can only be used for up to 24 hours while a Mental Health Act assessment is arranged.
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This question is part of the following fields:
- Psychiatry
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Question 4
Correct
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A 60-year-old man with a 20-year history of treatment with antipsychotic medications for bipolar disorder complains of the onset of writhing tongue and finger movements.
Which of the following is the most likely cause?Your Answer: Tardive dyskinesia
Explanation:Understanding Movement Disorders Associated with Anti-Psychotic Medication
Anti-psychotic medication can cause a range of movement disorders, including tardive dyskinesia, akathisia, and Parkinsonism. Tardive dyskinesia is a common side-effect of long-term treatment with anti-psychotics, but can also occur with minimal doses. It is characterized by choreoathetoid movements, often starting in the fingers and tongue and becoming more generalized. Treatment is often unsuccessful, but may involve switching to a different medication or using agents such as tetrabenazine or benzodiazepines. Akathisia is an inner feeling of motor restlessness, with voluntary movements such as pacing or rocking. Parkinsonism is characterized by resting tremor, rigidity, and bradykinesia. These movement disorders can be mistaken for other conditions such as Huntington’s or Wilson’s disease, but the association with anti-psychotic medication and the specific symptoms make tardive dyskinesia a more likely option. It is important for healthcare professionals to monitor patients on anti-psychotic medication for these potential side-effects and adjust treatment as necessary.
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This question is part of the following fields:
- Psychiatry
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Question 5
Correct
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A 17-year-old girl is brought to your clinic by her parents due to concerns about her weight loss (her BMI is now 18.5 kg/m2, down from 21 kg/m2 one year ago). You are familiar with the patient and have ruled out any physical causes for her weight loss. When you inquire about purging behaviors, such as self-induced vomiting, she appears hesitant to answer, but you notice that her tooth enamel is eroded. She expresses feeling extremely overweight and has been experiencing low mood for several months, finding little pleasure in anything except for when she indulges in too much chocolate and bread. However, afterwards, she feels even more disgusted with herself.
What is the most appropriate diagnosis for her condition?Your Answer: Bulimia nervosa
Explanation:Understanding Eating Disorders: Bulimia Nervosa
Bulimia nervosa is an eating disorder that is characterized by binge eating followed by purging behaviors such as vomiting, laxative abuse, excessive exercise, and drug use. Individuals with bulimia often experience feelings of loss of control and intense guilt during binge episodes. Pitting of tooth enamel caused by stomach acid is a common sign of regular vomiting. Unlike anorexia nervosa, bulimia is not usually associated with severe weight loss. The condition is ten times more common in women. It is important to recognize the symptoms of bulimia and seek professional help for proper diagnosis and treatment.
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This question is part of the following fields:
- Psychiatry
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Question 6
Incorrect
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A 25-year-old man presents to the clinic with persistent beliefs that his coworkers are plotting against him and trying to sabotage his work, despite reassurance and evidence to the contrary. He has had multiple heated arguments with his colleagues and after each one, he becomes aggressive and blames them for his outbursts. He sometimes feels like he cannot function without them, but also sometimes feels that they are out to get him. He has a history of a recent suicide attempt and has difficulties trusting his family as he feels they are part of the conspiracy. What is the most likely diagnosis?
Your Answer: Paranoid personality disorder
Correct Answer: Borderline personality disorder
Explanation:The young man in question is likely suffering from borderline personality disorder (BPD), also known as emotionally unstable personality disorder (EUPD). This condition is characterized by unstable relationships, alternating between idealization and devaluation of others, recurrent self-harm, unstable self-image and self-esteem, suicidal behavior, difficulty controlling anger, and efforts to avoid abandonment. All of these traits are present in this patient, making BPD the most likely diagnosis.
Narcissistic personality disorder is not a likely diagnosis for this patient, as it is characterized by a grandiose sense of self-importance, lack of empathy, and a sense of entitlement. These traits are not present in this patient, and his periods of devaluing her partner are temporary and not pervasive.
Dependent personality disorder is also an unlikely diagnosis, as this condition is characterized by a pervasive need for others to make decisions for the patient and constant reassurance. While the patient has felt that he cannot live without his partner in the past, his labile mood and alternating view of his partner make this diagnosis less likely.
Paranoid personality disorder is also an unlikely diagnosis, as patients with this condition tend to be reluctant to confide in others and have an unforgiving attitude when insulted or questioned. The patient in question does not exhibit these traits, and his difficulty with trusting friends is likely due to his belief that he is undeserving of them.
Personality disorders are a set of personality traits that are maladaptive and interfere with normal functioning in life. It is estimated that around 1 in 20 people have a personality disorder, which are typically categorized into three clusters: Cluster A, which includes Odd or Eccentric disorders such as Paranoid, Schizoid, and Schizotypal; Cluster B, which includes Dramatic, Emotional, or Erratic disorders such as Antisocial, Borderline (Emotionally Unstable), Histrionic, and Narcissistic; and Cluster C, which includes Anxious and Fearful disorders such as Obsessive-Compulsive, Avoidant, and Dependent.
Paranoid individuals exhibit hypersensitivity and an unforgiving attitude when insulted, a reluctance to confide in others, and a preoccupation with conspirational beliefs and hidden meanings. Schizoid individuals show indifference to praise and criticism, a preference for solitary activities, and emotional coldness. Schizotypal individuals exhibit odd beliefs and magical thinking, unusual perceptual disturbances, and inappropriate affect. Antisocial individuals fail to conform to social norms, deceive others, and exhibit impulsiveness, irritability, and aggressiveness. Borderline individuals exhibit unstable interpersonal relationships, impulsivity, and affective instability. Histrionic individuals exhibit inappropriate sexual seductiveness, a need to be the center of attention, and self-dramatization. Narcissistic individuals exhibit a grandiose sense of self-importance, lack of empathy, and excessive need for admiration. Obsessive-compulsive individuals are occupied with details, rules, and organization to the point of hampering completion of tasks. Avoidant individuals avoid interpersonal contact due to fears of criticism or rejection, while dependent individuals have difficulty making decisions without excessive reassurance from others.
Personality disorders are difficult to treat, but a number of approaches have been shown to help patients, including psychological therapies such as dialectical behavior therapy and treatment of any coexisting psychiatric conditions.
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This question is part of the following fields:
- Psychiatry
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Question 7
Incorrect
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A 65-year-old man with chronic schizophrenia complains of nausea and vomiting. He is given metoclopramide to alleviate his symptoms. However, after twenty minutes, he becomes restless and experiences severe oculogyric crises and oromandibular dystonia. What medication should be prescribed in this situation?
Your Answer: Lorazepam
Correct Answer: Procyclidine
Explanation:Procyclidine is the usual treatment for acute dystonia caused by antipsychotics. This patient’s acute dystonic reaction can be reversed with procyclidine, which is an anticholinergic medication that blocks acetylcholine. This medication can alleviate muscle stiffness, sweating, and excessive saliva production, and can also improve walking ability in individuals with Parkinson’s disease. The patient most likely developed this reaction due to long-term use of antipsychotics and subsequent administration of metoclopramide. While midazolam and lorazepam can relieve anxiety, they are not effective in treating dystonia.
Antipsychotics are a group of drugs used to treat schizophrenia, psychosis, mania, and agitation. They are divided into two categories: typical and atypical antipsychotics. The latter were developed to address the extrapyramidal side-effects associated with the first generation of typical antipsychotics. Typical antipsychotics work by blocking dopaminergic transmission in the mesolimbic pathways through dopamine D2 receptor antagonism. They are associated with extrapyramidal side-effects and hyperprolactinaemia, which are less common with atypical antipsychotics.
Extrapyramidal side-effects (EPSEs) are common with typical antipsychotics and include Parkinsonism, acute dystonia, sustained muscle contraction, akathisia, and tardive dyskinesia. The latter is a late onset of choreoathetoid movements that may be irreversible and occur in 40% of patients. The Medicines and Healthcare products Regulatory Agency has issued specific warnings when antipsychotics are used in elderly patients, including an increased risk of stroke and venous thromboembolism. Other side-effects include antimuscarinic effects, sedation, weight gain, raised prolactin, impaired glucose tolerance, neuroleptic malignant syndrome, reduced seizure threshold, and prolonged QT interval.
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This question is part of the following fields:
- Psychiatry
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Question 8
Correct
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A 40-year-old inpatient experienced an episode of acute psychosis. He was given a medication on the ward and later developed severe torticollis.
What is the most probable drug that was administered to the patient?Your Answer: Haloperidol
Explanation:Common Psychiatric Medications and Their Side-Effects
Haloperidol: A typical antipsychotic drug that can cause extrapyramidal side-effects (EPSEs), including acute dystonic reactions. Treatment is with anticholinergic drugs or benzodiazepines.
Clozapine: An atypical antipsychotic mainly used in treatment-resistant schizophrenia. Common side-effects include sedation, constipation, hypersalivation, weight gain, and metabolic syndrome. Rare but important side-effects include agranulocytosis, arrhythmias, and myocarditis. EPSEs are possible but rare.
Diazepam: A benzodiazepine used in anxiety, insomnia, seizures, and muscle spasms. Side-effects include sedation, muscle weakness, drowsiness, and confusion. EPSEs are not a recognised side-effect and may improve with the use of benzodiazepines.
Lithium: A mood stabiliser used in the treatment of mania, depression, and bipolar disorder. Side-effects include gastrointestinal disturbances, tremor, polydipsia, polyuria, and electrolyte disturbances. Lithium-induced hypothyroidism is common. EPSEs are not a side-effect of lithium.
Olanzapine: An atypical antipsychotic used in the treatment of schizophrenia and acute mania. Common side-effects include sedation, weight gain, and metabolic symptoms. EPSEs can occur but are not a typical side-effect of olanzapine.
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This question is part of the following fields:
- Psychiatry
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Question 9
Correct
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A 10-year-old girl is brought to the clinic by her parents due to ongoing disobedience towards her parents and other authority figures for the past three years. At school, she has frequently been involved in physical altercations with her peers and was recently reprimanded for damaging school property.
What is the most probable diagnosis?Your Answer: Conduct disorder
Explanation:Understanding Conduct Disorder and Differential Diagnoses
Conduct disorder is a psychiatric condition characterized by persistent and severe antisocial behaviors that violate social norms and the rights of others. These behaviors may include excessive fighting, cruelty to people or animals, destruction of property, persistent disobedience, and repeated lying. However, conduct disorder can be easily confused with other psychiatric conditions that present with similar symptoms. Here are some differential diagnoses to consider:
Depression: While depressive disorders can present with oppositional symptoms, they are usually accompanied by disturbances to appetite, sleep, and anhedonia, which are not seen in conduct disorder. However, depression can coexist with conduct disorder.
Adjustment reaction: Conduct disturbance can also be a reaction to an external stressor, such as divorce, bereavement, abuse, or trauma. However, these symptoms usually occur within three months of the stressor and can last up to six months. If there is no mention of an external stressor, conduct disorder is more likely.
Attention-deficit hyperactivity disorder (ADHD): Children with ADHD exhibit symptoms of inattention associated with hyperactivity and impulsiveness, which can affect social and academic functioning. However, unlike conduct disorder, these behaviors do not usually violate societal norms or the rights of others. ADHD can also coexist with conduct disorder.
Autism spectrum disorder: Children with autism spectrum disorder may present with emotional lability, aggressive outbursts, and destructive behavior, usually in response to an unexpected change in routine or sensory overload. However, there are typical features of autism, such as sensory hypersensitivity, that are not mentioned in conduct disorder. Autism can also coexist with conduct disorder.
In conclusion, conduct disorder is a serious psychiatric condition that requires early identification and intervention. However, it is important to consider other differential diagnoses to ensure accurate diagnosis and appropriate treatment.
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This question is part of the following fields:
- Psychiatry
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Question 10
Correct
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A 35-year-old man presents with symptoms of depression, difficulty sleeping, and a strong desire for sugary foods during the winter months. He reports that his symptoms are more severe in the winter than in the summer. He has no history of other mental health issues or physical problems. What is the most probable diagnosis?
Your Answer: Seasonal affective disorder (SAD)
Explanation:Differentiating Seasonal Affective Disorder from Other Depressive Disorders
Seasonal affective disorder (SAD) is a type of depression that occurs in a regular temporal pattern, typically beginning in autumn or winter and ending in spring or summer. Unlike classic major depression, SAD is characterized by symptoms of hyperphagia, hypersomnia, and weight gain. The cause of SAD is believed to be a malfunction of the light-sensitive hormone melatonin during winter. Treatment involves phototherapy, which exposes individuals to bright light for several hours a day.
Reactive depression, on the other hand, is a subtype of major depression that occurs as a result of an external event, such as a relationship breakdown or bereavement. There is no indication of a stressful life event in the presented vignette.
Bipolar affective disorder is characterized by distinct episodes of depression and mania, which is not evident in the vignette. Dysthymia is a persistent depression of mood that does not fully meet the criteria for a diagnosis of major depression and does not have a definite seasonal variation like SAD.
Finally, double depression occurs when one or more episodes of major depression occur on a background of dysthymia. It is important to differentiate SAD from other depressive disorders to provide appropriate treatment and management.
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This question is part of the following fields:
- Psychiatry
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